Dear Rain,
I used the Rhino software to create flat patterns, It was the software I was most comfortable with having used it for 3-D design for the last 8 years. I was also working at the time to create 3-D forms with the patterns using rapid-prototyping equipment.
Rhino wasn't needed to be able to feed the pattern into the laser cutter and I actually had to save my patterns as an adobe illustrator file to import them into the laser cutter. Which is an option available in the rhino program.
The laser cutter I was using was the property of the University of Washington's Architecture Department. I had access to the equipment when I was a graduate student and then as a faculty member when teaching in the Metals department of the School of Art at the University of Washington.
There are reprographic firms that service the architectural industry that have laser cutters and to have your own patterns cut it would be best to find a firm and ask them which software they prefer to guide you.
cheers,
Nanz